1. Neuronal Signaling
  2. Amyloid-β
  3. (Glu20)-Amyloid β-Protein (1-42)

(Glu20)-Amyloid β-Protein (1-42) 

目录号: HY-P3846
产品使用指南

(Glu20)-Amyloid β-Protein (1-42) 是淀粉样蛋白 β-蛋白 (Aβ) 的一种较慢原纤维化变体。Glu20 突变降低了 Aβ 的聚集倾向,从而防止缓慢原纤化肽的积累。β 淀粉样蛋白是阿尔茨海默病中血管和实质淀粉样沉积物的主要成分。

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Custom Peptide Synthesis

(Glu20)-Amyloid β-Protein (1-42) Chemical Structure

(Glu20)-Amyloid β-Protein (1-42) Chemical Structure

CAS No. : 1802086-22-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(Glu20)-Amyloid β-Protein (1-42) is a slower fibrillizing variant of amyloid β-protein (Aβ). The Glu20 mutation reduces the aggregation propensity of Aβ42 and prevents accumulation of the slowly fibrillizing peptide. Amyloid β-protein is the primary component of both vascular and parenchymal amyloid deposits in Alzheimer's disease[1][2].

分子量

4495.98

Formula

C199H309N55O62S

CAS 号
Sequence Shortening

DAEFRHDSGYEVHHQKLVFEAEDVGSNKGAIIGLMVGGVVIA

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

(Glu20)-Amyloid β-Protein (1-42) 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
(Glu20)-Amyloid β-Protein (1-42)
目录号:
HY-P3846
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