2. GPCR/G Protein
  3. GnRH Receptor
  4. GnRH Associated Peptide (1-24), human

GnRH Associated Peptide (1-24), human  (Synonyms: GAP (1-24), human)

目录号: HY-P3606
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GnRH Associated Peptide (GAP) (1-24), human 是人类促性腺激素释放激素相关肽 (GAP) 的 1-24 片段 (hGAP-1-24)。GAP 能够通过 3 个氨基酸加工位点与黄体生成素释放激素 (LH-RH) 序列相连。

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GnRH Associated Peptide (1-24), human Chemical Structure

GnRH Associated Peptide (1-24), human Chemical Structure

CAS No. : 148943-65-1

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GnRH Associated Peptide (1-24), human 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GnRH Associated Peptide (GAP) (1-24), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 1-24 fragment (hGAP-1-24). GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site[1].

体外研究
(In Vitro)

GAP (10 nM; 4 h) stimulates the release of both gonadotropins in anterior pituitaries from female Sprague-Dawley rats, but inhibits the basal secretion of prolactin by ~50%, compared with inhibition levels reported for dopamin, a known prolactin-inhibiting factor[2].
GAP (0.1-10 nM; 3-4 h) inhibits prolactin secretion by 40-45%, with an IC50 value of 0.25 nM[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

GnRH Associated Peptide (1-24), human 相关抗体:
分子量

2732.95

Formula

C117H190N32O43
CAS 号
Sequence Shortening

DAENLIDSFQEIVKEVGQLAETQR
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

GnRH Associated Peptide (1-24), human 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GnRH Associated Peptide (1-24), human148943-65-1GAP (1-24), humanGnRH ReceptorGonadotropin releasing hormone receptorGNRHRhuman gonadotropin-releasing hormone-associated peptideGAPimmunogenMC-1MC-2MC-3luteinizing hormone-releasing hormoneLH-RHInhibitorinhibitorinhibit

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