2. Metabolic Enzyme/Protease
  3. Aminotransferases (Transaminases)
  4. Gostatin

Gostatin 是一种天冬氨酸氨基转移酶 (GOT) 抑制剂。Gostatin 可在 Streptomyces sumanensis nov. sp. NK-23 中发现。Gostatin 对猪心 GOT 的抑制效果强，对小麦胚芽 GOT 和 GPT 的抑制效果较弱，对谷氨酸脱氢酶和谷氨酰胺合成酶无显著影响。Gostatin 的抑制机制类似于底物竞争性抑制，天冬氨酸对其抑制作用具有保护效应。Gostatin 可用于研究 GOT 的催化机制及其在氮代谢中的作用。

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Gostatin

Gostatin Chemical Structure

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Gostatin 相关抗体

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GPT/ALT GOT/AST

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Gostatin is an inhibitor of aspartate aminotransferase (GOT). Gostatin is found in Streptomyces sumanensis nov. sp. NK-23. Gostatin has a strong inhibitory effect on pig heart GOT, a weak inhibitory effect on wheat germ GOT and GPT, and no significant effect on glutamate dehydrogenase and glutamine synthetase. The inhibitory mechanism of gostatin is similar to substrate competitive inhibition, and aspartate has a protective effect on its inhibitory effect. Gostatin can be used to study the catalytic mechanism of GOT and its role in nitrogen metabolism[1].

分子量

214.18

Formula

C8H10N2O5
结构分类
初始来源

Streptomyces sumanensis nov. sp.
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Gostatin 相关分类

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  • 稀释计算器

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GostatinGostatineAminotransferases (Transaminases)GOTGPTInhibitorinhibitorinhibit

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