1. Anti-infection
  2. RABV
  3. GRP-60367

GRP-60367 是种首创的小分子狂犬病病毒 (RABV) 进入抑制剂,对某些 RABV 株具有纳摩尔作用效果。

在相同的摩尔浓度下,化合物盐形式与游离形式有相同的生物活性,但盐形式 GRP-60367 hydrochloride 通常具有更好的水溶性和稳定性。

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GRP-60367 Chemical Structure

GRP-60367 Chemical Structure

CAS No. : 1309241-34-6

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     可免费申领三个不同产品的试用装。

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规格 是否有货
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100 mg   询价  
250 mg   询价  

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GRP-60367 的其他形式现货产品:

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GRP-60367 is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains[1].

体外研究
(In Vitro)

GRP-60367 inhibits entry of a subset of RABV strains. GRP-60367 shows specific and potent anti-RABV activity of the scaffold, returning in dose-response assays EC50s ranging from 2 to 52 nM on different host cell lines[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

353.46

Formula

C21H27N3O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

GRP-60367 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
GRP-60367
目录号:
HY-133735
需求量: