2. PROTAC
  3. PROTAC Linker
  4. HO-PEG8-CH2CH2COOH

HO-PEG8-CH2CH2COOH (Synonyms: Hydroxy-PEG8-acid)

目录号: HY-133053
产品使用指南

HO-PEG8-CH2CH2COOH (Hydroxy-PEG8-acid) 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

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HO-PEG8-CH2CH2COOH Chemical Structure

HO-PEG8-CH2CH2COOH Chemical Structure

CAS No. : 937188-60-8

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Description

HO-PEG8-CH2CH2COOH (Hydroxy-PEG8-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Molecular Weight

442.50

Formula

C₁₉H₃₈O₁₁
CAS No.

937188-60-8
SMILES

O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
References

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

HO-PEG8-CH2CH2COOHHydroxy-PEG8-acidPROTAC LinkerInhibitorinhibitorinhibit

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产品名称：
HO-PEG8-CH2CH2COOH
目录号：
HY-133053
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