2. Metabolic Enzyme/Protease
  3. 17β-HSD
  4. HSD17B13-IN-36

HSD17B13-IN-36 (compound 116) 是羟基类固醇 17?-脱氢酶13 (HSD17B13) ( hydroxysteroid 17?-dehydrogenase 13 (HSD17B13)) 的有效抑制剂，雌二醇作为底物的 IC50? 小于 0.1 μM。HSD17B13-IN-36 在包括 NASH（非酒精性脂肪性肝炎）在内的非酒精性脂肪肝疾病 (NAFLD) 的研究中发挥着重要作用。

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HSD17B13-IN-36 Chemical Structure

HSD17B13-IN-36 Chemical Structure

CAS No. : 2730027-86-6

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HSD17B13-IN-36 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HSD17B13-IN-36 (compound 116) is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC50 of ＜ 0.1 μM? estradiol? as substrates. HSD17B13-IN-36? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis)[1].

分子量

433.43

Formula

C20H17F2N3O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HSD17B13-IN-36 相关分类

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Keywords:

HSD17B13-IN-362730027-86-617β-HSD17beta-HSD17β-hydroxysteroid dehydrogenases17 beta-hydroxysteroid dehydrogenasenonalcoholic fatty liver diseases (NAFLDs),? NASH (nonalcoholic steatohepatitis)Inhibitorinhibitorinhibit

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