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  4. Human CXCR2 mRNA

Human CXCR2 mRNA 编码人类 CXC 基序趋化因子受体 2 (CXCR2) 蛋白，该蛋白属于 G 蛋白偶联受体家族。CXCR2 是白细胞介素 8 (IL8) 的受体。它与 IL8 具有高亲和力结合，并通过 G 蛋白激活的第二信使系统传递信号。该受体也与趋化因子（CXC 基序）配体 1 (CXCL1/MGSA) 结合，后者是一种具有黑色素瘤生长刺激活性的蛋白质，已被证明是血清依赖性黑色素瘤细胞生长所需的主要成分。

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Human CXCR2 mRNA

Human CXCR2 mRNA Chemical Structure

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Human CXCR2 mRNA 相关抗体

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  • 生物活性

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生物活性

Human CXCR2 mRNA encodes the human C-X-C motif chemokine receptor 2 (CXCR2) protein, a member of the G-protein-coupled receptor family. CXCR2 is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth.

种属

Human

基因 ID

3579  [NCBI]

基因信息

CXCR2 - C-X-C motif chemokine receptor 2

同用名

CD182; IL8R2; IL8RA; IL8RB; CMKAR2; WHIMS2; CDw128b

Sequence

MGTEATEQVS WGHYSGDEED AYSAEPLPEL CYKADVQAFS RAFQPSVSLT VAALGLAGNG LVLATHLAAR RAARSPTSAH LLQLALADLL LALTLPFAAA GALQGWSLGS ATCRTISGLY SASFHAGFLF LACISADRYV AIARALPAGP RPSTPGRAHL VSVIVWLLSL LLALPALLFS QDGQREGQRR CRLIFPEGLT QTVKGASAVA QVALGFALPL GVMVACYALL GRTLLAARGP ERRRALRVVV ALVAAFVVLQ LPYSLALLLD TADLLAARER SCPASKRKDV ALLVTSGLAL ARCGLNPVLY AFLGLRFRQD LRRLLRGGSC PSGPQPRRGC PRRPRLSSCS APTETHSLSW DN
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Human CXCR2 mRNA 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Human CXCR2 mRNAmRNAmessenger RNAInhibitorinhibitorinhibit

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Human CXCR2 mRNA
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