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  4. Human EIF2AK2 mRNA

Human EIF2AK2 mRNA编码人类真核翻译起始因子2α激酶2（EIF2AK2）蛋白，该蛋白是一种丝氨酸/苏氨酸蛋白激酶，与dsRNA结合后通过自身磷酸化激活。EIF2AK2在病毒感染的先天免疫反应中起关键作用，并参与信号转导、细胞凋亡、细胞增殖和分化的调控。

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Human EIF2AK2 mRNA

Human EIF2AK2 mRNA Chemical Structure

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Human EIF2AK2 mRNA 相关抗体

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  • 生物活性

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生物活性

Human EIF2AK2 mRNA encodes the human eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2) protein, a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. EIF2AK2 plays a key role in the innate immune response to viral infection and is also involved in the regulation of signal transduction, apoptosis, cell proliferation and differentiation.

种属

Human

基因 ID

5610  [NCBI]

基因信息

EIF2AK2 - eukaryotic translation initiation factor 2 alpha kinase 2

同用名

PKR; PRKR; DYT33; LEUDEN; EIF2AK1; PPP1R83

Sequence

MTPTDFTSPI PNMADDYGSE STSSMEDYVN FNFTDFYCEK NNVRQFASHF LPPLYWLVFI VGALGNSLVI LVYWYCTRVK TMTDMFLLNL AIADLLFLVT LPFWAIAAAD QWKFQTFMCK VVNSMYKMNF YSCVLLIMCI SVDRYIAIAQ AMRAHTWREK RLLYSKMVCF TIWVLAAALC IPEILYSQIK EESGIAICTM VYPSDESTKL KSAVLTLKVI LGFFLPFVVM ACCYTIIIHT LIQAKKSSKH KALKVTITVL TVFVLSQFPY NCILLVQTID AYAMFISNCA VSTNIDICFQ VTQTIAFFHS CLNPVLYVFV GERFRRDLVK TLKNLGCISQ AQWVSFTRRE GSLKLSSMLL ETTSGALSL
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Human EIF2AK2 mRNA 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Human EIF2AK2 mRNAmRNAmessenger RNAInhibitorinhibitorinhibit

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Human EIF2AK2 mRNA
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