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  3. Human TFE3 mRNA

Human TFE3 mRNA 能编码一种与 IGHM 增强子 3 结合的人类转录因子(即 TFE3 蛋白),这是一种包含基本螺旋-环-螺旋结构域的转录因子,能够结合 MUE3 型 E-box 序列。TFE3 可能与肾细胞癌及其他癌症中的染色体易位有关,从而导致融合蛋白的产生。

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Human TFE3 mRNA

Human TFE3 mRNA Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

生物活性

Human TFE3 mRNA encodes the human transcription factor binding to IGHM enhancer 3 (TFE3) protein, a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences. TFE3 may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins.

种属

Human

基因 ID

7030  [NCBI]

基因信息

TFE3 - transcription factor binding to IGHM enhancer 3

同用名

TFEA; RCCP2; RCCX1; MRXSPF; bHLHe33

Sequence

MAALPGTVPR MMRPAPGQNY PRTGFPLEVS TPLGQGRVNQ LGGVFINGRP LPNHIRHKIV EMAHHGIRPC VISRQLRVSH GCVSKILCRY QETGSIRPGA IGGSKPRQVA TPDVEKKIEE YKRENPGMFS WEIRDRLLKD GHCDRSTVPS GLVSSISRVL RIKFGKKEEE DEADKKEDDG EKKAKHSIDG ILGDKGNRLD EGSDVESEPD LPLKRKQRRS RTTFTAEQLE ELEKAFERTH YPDIYTREEL AQRTKLTEAR VQVWFSNRRA RWRKQAGANQ LAAFNHLLPG GFPPTGMPTL PPYQLPDSTY PTTTISQDGG STVHRPQPLP PSTMHQGGLA AAAAAADTSS AYGARHSFSS YSDSFMNPAA PSNHMNPVSN GLSPQVMSIL GNPSAVPPQP QADFSISPLH GGLDSATSIS ASCSQRADSI KPGDSLPTSQ AYCPPTYSTT GYSVDPVAGY QYGQYGQTAV DYLAKNVSLS TQRRMKLGEH SAVLGLLPVE TGQAY

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Human TFE3 mRNA
目录号:
HY-174536
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