1. Anti-infection
  2. Influenza Virus
  3. Influenza virus-IN-10

Influenza virus-IN-10 是一种双靶点抗流感病毒药物,可同时靶向 PAC (KD = 8.9 μM) 和 NP (KD = 52.5 μM)。Influenza virus-IN-10 对甲型流感病毒 (H1N1, A/WSN/33) 的 EC50 值为 1.64 μM,并对其他流感病毒株,包括乙型流感病毒和多种甲型流感病毒亚型,具有广谱活性。

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Influenza virus-IN-10

Influenza virus-IN-10 Chemical Structure

CAS No. : 3031321-95-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Influenza virus-IN-10 is a dual-target antiviral agents for influenza that targets both PAC (KD = 8.9 μM) and NP (KD = 52.5 μM) simultaneously. Influenza virus-IN-10 exhibits an EC50 values of 1.64 μM) against influenza A virus (H1N1, A/WSN/33) and broad-spectrum activity against other influenza strains, including influenza B virus and multiple subtypes of influenza A[1].

体外研究
(In Vitro)

Influenza virus-IN-10 (Compound 8e) 对 A/HK/68 (IC50 = 8.09 μM) 和 A/PR/8 (IC50 = 7.54 μM) 均表现出抑制活性[1]
Influenza virus-IN-10 与蛋白酶 K 和小鼠血清孵育 48 小时后仍保持稳定[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

426.51

Formula

C26H26N4O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Influenza virus-IN-10 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Influenza virus-IN-10
目录号:
HY-178455
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