2. Immunology/Inflammation
  3. Complement System
  4. IONIS-FB-LRx

IONIS-FB-LRx  (Synonyms: RG6299)

目录号: HY-148370
产品使用指南

摩尔计算器

IONIS-FB-LRx 是一种靶向补体因子 B (CFB) 的特殊反义寡核苷酸(ASO)。IONIS-FB-LRx 能有效降低 CFB 的循环水平。IONIS-FB-LRx可用于地理萎缩 (GA) 研究。

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DNA, d(P-thio)([2′-O-(2-methoxyethyl)]rA-[2′-O-(2-methoxyethyl)]m5rU-[2′-O-(2-methoxyethyl)]m5rC-[2′-O-(2-methoxyethyl)]m5rC-[2′-O-(2-methoxyethyl)]m5rC-A-m5C-G-m5C-m5C-m5C-m5C-T-G-T-[2′-O-(2-methoxyethyl)]m5rC-[2′-O-(2-methoxyethyl)]m5rC-[2′-O-(2-methoxyethyl)]rA-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]m5rC), 5′-[26-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[6-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]hexyl]amino]-3-oxopropoxy]methyl]-8,12,19-trioxo-16-oxa-7,13,20-triazahexacos-1-yl hydrogen phosphate]

IONIS-FB-LRx Chemical Structure

CAS No. : 2272975-74-1

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规格 价格 是否有货 数量
1 mg ￥5100
5 - 7 周
5 mg   询价  
10 mg   询价  

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Customer Review

IONIS-FB-LRx 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

IONIS-FB-LRx is a specific antisense oligonucleotide (ASO) targeting complement factor B (CFB). IONIS-FB-LRx effectively reduces circulating levels of CFB. IONIS-FB-LRx can be used for geographic atrophy (GA) research[1][2].

IC50 & Target

Complement factor B (CFB)[1]
体内研究
(In Vivo)

IONIS-FB-Lrx is administered by subcutaneous injection every four weeks and targets CFB’s hepatic expression[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

9056.30

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

IONIS-FB-LRx 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IONIS-FB-LRx2272975-74-1RG6299RG 6299RG-6299Complement Systemgeographic atrophyage-related macular degenerationcomplement factor BInhibitorinhibitorinhibit

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目录号：
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