2. Apoptosis
  3. Apoptosis
  4. Isodispar B

Isodispar B 是一种抗癌剂，抑制鼻咽癌和乳腺癌细胞增殖，诱导细胞凋亡 (apoptosis)。Isodispar B 对广泛的癌细胞系具有细胞毒性。

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Isodispar B Chemical Structure

Isodispar B Chemical Structure

CAS No. : 98192-64-4

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Isodispar B 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Isodispar B is an anticancer agent that inhibits the proliferation of nasopharyngeal carcinoma and breast cancer cells and induces cell apoptosis. Isodispar B is cytotoxic to a wide range of cancer cell lines[1].

体外研究
(In Vitro)

Isodispar B (化合物 1) (0-100 μM; 72 h) 具有广谱的抗癌活性，抑制细胞增殖，IC50 为 3.84-56.73 μM[1]。
Isodispar B (1 μM 和 10 μM; 3 d) 诱导鼻咽癌细胞 (TW01、CNE1、HK1、SUNE1) 凋亡[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Isodispar B 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: Nasopharyngeal cancer cells (TW01, CNE1, HK1, and SUNE1) and noncancerous nasopharyngeal cells (NP460)
Concentration: 0-100 μM
Incubation Time: 72 hours
Result: Showed cytotoxicity and inhibited cell viability with IC50s of 3.84 μM (SUNE1), 11.49 μM (TW01), 9.74 μM (CNE1), 5.58 μM (HK1), 56.73 μM (HCC38), 52.69 μM (MDA-MB-231), 52.75 μM (MDA-ME-468), and 54.85 μM (SKBR3), respectively.
分子量

338.35

Formula

C20H18O5
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Isodispar B 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isodispar B98192-64-4ApoptosisInhibitorinhibitorinhibit

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