2. GPCR/G Protein
  3. Kisspeptin Receptor
  4. Kisspeptin antagonist p271

Kisspeptin antagonist p271 是一种 Kisspeptin 拮抗剂，具有细胞穿透能力。Kisspeptin antagonist p271 可阻断内源性 Kisspeptin 与垂体生长激素细胞上 GPR54 的结合以解除对生长激素分泌的抑制。Kisspeptin antagonist p271 能特异性显著刺激生长激素分泌，同时抑制促黄体生成素，且不影响催乳素、皮质醇。Kisspeptin antagonist p271 可用于生长激素分泌不足相关疾病的研究。

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Kisspeptin antagonist p271

Kisspeptin antagonist p271 Chemical Structure

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Kisspeptin antagonist p271 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Kisspeptin antagonist p271 is a Kisspeptin antagonist with cell-penetrating ability. Kisspeptin antagonist p271 can block the binding of endogenous Kisspeptin to GPR54 on pituitary somatotropes, thereby relieving the inhibition of growth hormone secretion. Kisspeptin antagonist p271 can specifically and significantly stimulate growth hormone secretion, while inhibiting luteinizing hormone without affecting prolactin or cortisol. Kisspeptin antagonist p271 can be used in the research of diseases related to insufficient GH secretion[1].

分子量

2430.84

Formula

C116H164N36O21S
Sequence

Arg-Arg-Met-Lys-Trp-Lys-Lys-Tyr-{D-Ala}-Asn-Trp-Asn-Gly-Phe-Gly-{D-Trp}-Arg-Phe-NH2
Sequence Shortening

RRMKWKKY-{D-Ala}-NWNGFG-{D-Trp}-RF-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Kisspeptin antagonist p271 相关分类

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kisspeptin antagonist p271Kisspeptin antagonist p 271Kisspeptin antagonist p-271Kisspeptin ReceptorKiss1RGPR54ewesInhibitorinhibitorinhibit

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目录号：
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