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  4. LDN193189 hydrochloride

LDN193189 hydrochloride  (Synonyms: DM-3189 hydrochloride)

目录号: HY-12071C
产品使用指南 技术支持

LDN193189 (hydrochloride) 是一种生化试剂，可作为生物材料或有机化合物，用于生命科学相关研究。

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LDN193189 hydrochloride

LDN193189 hydrochloride Chemical Structure

CAS No. : 1062368-62-0

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3.  试用装只面向终端客户。

规格 价格 是否有货 数量
5 mg ￥1040
1 - 2 周
10 mg ￥1533
1 - 2 周
25 mg ￥2847
1 - 2 周
50 mg ￥4234
1 - 2 周
100 mg 询价 1 - 2 周
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

Other Forms of LDN193189 hydrochloride:

LDN193189 hydrochloride 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 60 篇科研文献

IHC
WB

    LDN193189 hydrochloride purchased from MCE. Usage Cited in: Oxid Med Cell Longev. 2020 Jun 8;2020:4175613.  [Abstract]

    Western blot and grey analysis of CYP11a1, CYP19a1, BCL2, CALR, CHOP, caspase3, caspase12, PERK, and GRP78. qRT-PCR analyzed ATF4, caspase3, and GRP78 mRNAs. The relieving function of BMP4 on ER stress is diminished after blockade of BMP receptor I (BMPRI) with DM-3189.

    LDN193189 hydrochloride purchased from MCE. Usage Cited in: Cardiovasc Toxicol. 2019 Jun;19(3):264-275.  [Abstract]

    H9c2 cells are treated as following: control, DOX, DOX + rhBMP (Bmpr1a agonist) and DOX + LDN193189 (Bmpr1a inhibitor). Cells with red fluorescence indicate favorable MMP while green fluorescence indicates damage.

    • 生物活性

    • 纯度 & 产品资料

    生物活性

    LDN193189 (hydrochloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

    体外研究
    (In Vitro)

    LDN193189 HCl 是 ldn193189 的盐酸盐。LDN193189 是一种高效的小分子 BMP 抑制剂，可抑制 BMP I 型受体 ALK2（IC50：5 nM）、ALK3（IC50：30 nM）和 ALK6（TGFβ1/BMP 信号）和随后的 SMAD 磷酸化。

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.

    LDN193189 hydrochloride 相关抗体:
    分子量

    442.94

    Formula

    C25H23ClN6
    CAS 号
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.
    纯度 & 产品资料

    LDN193189 hydrochloride 相关分类

    • 摩尔计算器

    • 稀释计算器

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    质量   浓度   体积   分子量 *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    LDN1931891062368-62-0DM-3189LDN 193189LDN-193189DM3189DM 3189Biochemical Assay Reagentsbiochemical reagentbiological materialorganic compoundlife scienceInhibitorinhibitorinhibit

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    目录号：
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