1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Lipoxin B4

Lipoxin B4 (LXB4) 是一种结构独特的花生四烯酸代谢产物。Lipoxin B4 减少上呼吸道中的鼻粘膜中的白细胞浸润和粘液分泌,并减少肥大细胞和嗜酸性粒细胞脱颗粒。Lipoxin B4 可减少下呼吸道炎症、粘液化生和高反应性。Lipoxin B4 具有粘膜保护作用,具有研究上、下呼吸道过敏性炎症的潜力。

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Lipoxin B4 Chemical Structure

Lipoxin B4 Chemical Structure

CAS No. : 98049-69-5

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lipoxin B4 (LXB4) is a structurally distinct product of arachidonic acid metabolism. Lipoxin B4 reduces leukocyte infiltration and mucus secretion in the nasal mucosa and decreases mast cell and eosinophil degranulation in the upper airway. Lipoxin B4 decreases airway inflammation, mucus metaplasia and hyper- responsiveness in the lower airway. Lipoxin B4 shows mucosal protective actions and has the potential for the research of allergic inflammation in the upper and lower airways[1].

IC50 & Target

Human Endogenous Metabolite

 

分子量

352.47

Formula

C20H32O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Lipoxin B4
目录号:
HY-116953
需求量: