2. GPCR/G Protein
  3. Leukotriene Receptor
  4. LTB4 antagonist 2

LTB4 antagonist 2 是一种甲酰胺酸化合物，是白三烯 B4 (LTB4) 的拮抗剂，具有潜在抗炎活性。 LTB4 antagonist 2 对 LTB4 受体具有良好的亲和力，IC50 为 439 nM。

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LTB4 antagonist 2 Chemical Structure

LTB4 antagonist 2 Chemical Structure

CAS No. : 2929239-85-8

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LTB4 antagonist 2 相关抗体

Top Publications Citing Use of Products

查看 Leukotriene Receptor 亚型特异性产品:

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LTB4 LTC4/CysLT2 LTD4/CysLT1 LTE4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LTB4 antagonist 2, a carboxamide-acid compound, is an antagonist of leukotriene B4 (LTB4) with potentially anti-inflammatory activity. LTB4 antagonist 2 shows good affinity for the LTB4 receptor with IC50 of 439 nM[1].

IC50 & Target[1]

LTB4

439 nM (IC50)

体外研究
(In Vitro)

LTB4 antagonist 2 (compound 24c) (0.1 μM，10 μM) 显示特异性结合 LTB4 的抑制作用，在 0.1 μM 和 10 μM 时分别具有 25% 和 95% 的抑制率[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

LTB4 antagonist 2 相关抗体:
分子量

445.46

Formula

C26H23NO6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LTB4 antagonist 2 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LTB4 antagonist 22929239-85-8Leukotriene Receptoranti-inflammatorycarboxamide-acid compoundInhibitorinhibitorinhibit

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