1. Metabolic Enzyme/Protease
  2. LXR
  3. LXRβ agonist-2

LXRβ agonist-2 

目录号: HY-100469
产品使用指南

LXRβ agonist-2 是一种高效 β 选择性肝 X 受体 (LXRβ) 激动剂,EC50为 7 nM,其选择性是 LXRα (EC50=200 nM) 的 28.5 倍,用于治疗动脉粥样硬化。

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LXRβ agonist-2 Chemical Structure

LXRβ agonist-2 Chemical Structure

CAS No. : 1949801-52-8

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Description

LXRβ agonist-2 is a highly potent and β-selective liver X receptor (LXRβ) agonist with EC50 of 7 nM, displays 28.5-fold selectivity over LXRα (EC50=200 nM) and used in the treatment of atherosclerosis[1].

IC50 & Target

EC50: 7 nM (LXRβ), 200 nM (LXRα)[1]

Molecular Weight

683.59

Formula

C₃₂H₃₁F₆N₃O₇

CAS No.

1949801-52-8

SMILES

OC(C(F)(F)F)(C(F)(F)F)C1=CC(CCC)=C(OC2=CC(O)=C(C(CN3C(NC(C)(C4=NC=C(OC(C)C)C=C4)C3=O)=O)=O)C=C2)C=C1

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
LXRβ agonist-2
目录号:
HY-100469
需求量:

LXRβ agonist-2

Cat. No.: HY-100469