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  3. Mal-Cyclohexyl-PEG3-Biotin

Mal-Cyclohexyl-PEG3-Biotin 是一种含有马来酰亚胺部分和生物素基团的 PEG 连接体。当 pH 值介于 6.5 和 7.5 之间时,马来酰亚胺会与巯基发生特异性反应,形成稳定的硫醚键。在活化剂 EDC 或 HATU 存在下,生物素化可以与胺分子发生反应。与生物素连接的 PEG 会产生延长的间隔臂,使生物素能够进入蛋白质的结合位点。PEG 部分还大大增加了生物素-PEG 结合物的溶解度。

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Mal-Cyclohexyl-PEG3-Biotin

Mal-Cyclohexyl-PEG3-Biotin Chemical Structure

CAS No. : 2639395-45-0

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  • 生物活性

  • 纯度 & 产品资料

生物活性

Mal-Cyclohexyl-PEG3-Biotin is a PEG linker containing a maleimide moiety and a biotin group. Maleimides react specifically with sulfhydryl groups to form a stable thioether linkage when the pH is between 6.5 and 7.5. The biotinylation can react with amine molecules in the presence of activator EDC or HATU. PEG attached to the biotin gives an extended spacer arm that permits the biotin to reach into the binding pocket of the protein. The PEG moiety also increases solubility of Biotin-PEG conjugates considerably.

分子量

637.79

Formula

C30H47N5O8S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料

Mal-Cyclohexyl-PEG3-Biotin 相关分类

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产品名称:
Mal-Cyclohexyl-PEG3-Biotin
目录号:
HY-W800679
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