2. Anti-infection Apoptosis Autophagy NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  3. Parasite Apoptosis Autophagy Reactive Oxygen Species
  4. Mammea A/BA

Mammea A/BA 对克氏锥虫 (T. cruzi) 具有有效的抗性。Mammea A/BA 诱导线粒体功能障碍、产生活性氧 (ROS) 和 DNA 片段化，并增加酸性液泡数量。Mammea A/BA 可诱导细胞凋亡 (apoptosis)、细胞自噬 (autophagy) 和细胞坏死。Mammea A/BA 可用于南美锥虫病的研究

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Mammea A/BA Chemical Structure

Mammea A/BA Chemical Structure

CAS No. : 5224-54-4

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Mammea A/BA 相关抗体

Top Publications Citing Use of Products

查看 Parasite 亚型特异性产品:

查看所有亚型
Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Mammea A/BA has potent activity against Trypanosoma cruzi (T. cruzi). Mammea A/BA induces mitochondrial dysfunction, reactive oxygen species (ROS) production and DNA fragmentation, and increases number of acidic vacuoles. Mammea A/BA can induce apoptosis, autophagy and necrosis. Mammea A/BA can be used for researching chagas disease[1].

IC50 & Target

T. cruzi[1]
分子量

406.47

Formula

C25H26O5
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Mammea A/BA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mammea A/BA5224-54-4ParasiteApoptosisAutophagyReactive Oxygen SpeciesT. cruzichagas diseaseInhibitorinhibitorinhibit

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