2. Immunology/Inflammation
  3. Complement System
  4. MEDI7814

MEDI7814 是一种靶向 C5a 和 C5adesArg 的人源化单克隆抗体抑制剂。MEDI7814 与重组人 C5a 和血清纯化的人 C5a 的结合亲和力分别为 14 pM 和 8 pM。MEDI7814 有望用于急性炎症疾病，如败血症和肾缺血再灌注损伤。

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MEDI7814

MEDI7814 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
1 mg   询价  
5 mg   询价  
10 mg   询价  

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Customer Review

MEDI7814 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MEDI7814 is a humanized monoclonal antibody inhibitor targeting C5a and C5adesArg. MEDI7814 binds to recombinant human C5a and serum purified human C5a with affinities of 14 pM and 8 pM, respectively. MEDI7814 is acute inflammatory diseases such as sepsis and renal ischemia-reperfusion injury[1].

同型

Human IgG4 kappa
推荐同型对照抗体
反应种属

Human
IC50 & Target

Complement C5
基因 ID

727  [NCBI]

Accession
靶点

Complement C5
应用

ELISA, FACS, Functional assay
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MEDI7814 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MEDI7814MEDI 7814MEDI-7814Complement SystemC5aC5adesArgacute inflammatory conditionsInhibitorinhibitorinhibit

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产品名称：
MEDI7814
目录号：
HY-P991657
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