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  3. Melan-A/MART-1 analog

Melan-A/MART-1 analog  (Synonyms: [Leu27]-Melan-A, MART-1 (26-35))

目录号: HY-P5471
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摩尔计算器

Melan-A/MART-1 analog ([Leu27]-Melan-A, MART-1 (26-35)) 是一种有生物活性的肽。(这种 Melan-A (26-35) 类似物（第 27 位由 Leu 取代 Ala）显示出比天然 Melan-A (26-35) 更好的 HLA-A*0201 结合特性以及更好的免疫原性和抗原性。 焦谷氨酰 (pGlu)当谷氨酰胺 (Q) 或谷氨酸 (E) 位于序列 N 末端时，肽可能会自发形成。 Q或E向pGlu的转化是自然发生的，并且一般认为pGlu的疏水性γ-内酰胺环可能在针对胃肠道蛋白酶的肽稳定性中发挥作用。因此，焦谷氨酰肽被认为是此类肽的正常子集，并在 HPLC 分析期间作为肽纯度的一部分包含在内。)

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Custom Peptide Synthesis

Melan-A/MART-1 analog Chemical Structure

Melan-A/MART-1 analog Chemical Structure

CAS No. : 204060-45-7

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Melan-A/MART-1 analog 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

Melan-A/MART-1 analog ([Leu27]-Melan-A, MART-1 (26-35)) is a biological active peptide. (This Melan-A (26-35) analog, Leu substituted for Ala at position 27, shows better HLA-A*0201 binding properties as well as better immunogenicity and antigenicity than the natural Melan-A (26-35).Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)

分子量

985.18

Formula

C45H80N10O14
CAS 号
Sequence

Glu-Leu-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val
Sequence Shortening

ELAGIGILTV
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Melan-A/MART-1204060-45-7[Leu27]-Melan-A, MART-1 (26-35)OthersInhibitorinhibitorinhibit

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