2. Antibody-drug Conjugate/ADC Related
  3. Peptide-Drug Conjugates (PDCs)
  4. NHS-activated 2-octynoic acid-BSA

NHS-activated 2-octynoic acid-BSA 是一种免疫原，用于建立小鼠原发性胆管炎 (PBC) 模型。NHS-activated 2-octynoic acid-BSA 与 Complete Freund's Adjuvant (HY-153808) 联合使用，刺激身体的免疫系统，使免疫系统将其识别为外来抗原，并触发针对自身胆道上皮细胞的免疫反应。这导致抗 PDC-E2 抗体的产生，导致胆管损伤和炎症。NHS-activated 2-octynoic acid-BSA 有望用于原发性胆管炎的研究。

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NHS-activated 2-octynoic acid-BSA Chemical Structure

NHS-activated 2-octynoic acid-BSA Chemical Structure

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NHS-activated 2-octynoic acid-BSA 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NHS-activated 2-octynoic acid-BSA is an immunogen used to establish a murine model of primary biliary cholangitis (PBC). NHS-activated 2-octynoic acid-BSA works in conjunction with Complete Freund's Adjuvant (HY-153808) to stimulate the body's immune system, causing the immune system to recognize it as a foreign antigen and trigger an immune response against autologous biliary epithelial cells. This leads to the production of anti-PDC-E2 antibodies, resulting in bile duct damage and inflammation. NHS-activated 2-octynoic acid-BSA is promising for research of primary biliary cholangitis[1][2].

性状

液体

运输条件

Shipping with dry ice.
储存方式

-80°C, protect from light
纯度 & 产品资料
参考文献

NHS-activated 2-octynoic acid-BSA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NHS-activated 2-octynoic acid-BSAPeptide-Drug Conjugates (PDCs)Immunogenbody's immune systemPDC-E2Inhibitorinhibitorinhibit

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