1. Anti-infection
  2. Bacterial
  3. Olanexidine

Olanexidine  (Synonyms: 奥兰西丁)

目录号: HY-125654
产品使用指南

Olanexidine 是一种抗菌剂。Olanexidine 对多种细菌都有抗菌活性,包括革兰氏阳性和革兰氏阴性细菌。Olanexidine 也是一种防腐剂。Olanexidine 可用于感染和炎症的研究。

在相同的摩尔浓度下,化合物盐形式与游离形式有相同的生物活性,但盐形式 Olanexidine hydrochloride 通常具有更好的水溶性和稳定性。

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Olanexidine Chemical Structure

Olanexidine Chemical Structure

CAS No. : 146510-36-3

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Olanexidine 的其他形式现货产品:

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Olanexidine is an antibacterial agent. Olanexidine is active against a wide range of bacteria, imcluding both Gram-positive and Gram-negative bacteria Olanexidine is also an antiseptic. Olanexidine can be used in the research of infection and inflammation[1][2][3].

体外研究
(In Vitro)

Olanexidine (50 μM, 48 h) exhibits broad-spectrum bactericidal activity against Gram-positive cocci and Gram-negative bacteria[1].
Olanexidine (50 μg/mL, 24 h) inhibits chronic inflammatory reactions in oral mucosal cells[2].
Olanexidine (Olanexidine gluconate, 0-15000 μg/mL) inhibits the binding ability of virus-like particles to the binding receptor of human norovirus and increases the aggregation of virus-like particles[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: Gram-positive cocci, Enterococcus spp., Gram-positive bacilli, Gram-negative strains
Concentration: 0-1 mg/mL approximately
Incubation Time: 30 s
Result: Inhibited bacterial activity with MIC values ranging from 6.8 to 1740 μg/mL approximately.
体内研究
(In Vivo)

Olanexidine (1 -2% in saline, applied to the skin) is active against transient or resident bacterial flora on the skin of male cynomolgus monkeys[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male cynomolgus monkeys[4]
Dosage: 1 %, 1.5%, 2% in saline
Administration: Applied to the skin
Result: Showed the fast-acting and long-lasting bactericidal effects at 1.5% concentration.
分子量

372.34

Formula

C17H27Cl2N5

CAS 号
中文名称

奥兰西丁

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Olanexidine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Olanexidine
目录号:
HY-125654
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