1. Immunology/Inflammation
  2. MHC
  3. PADRE peptide

PADRE peptide 是一种通用肽表位。PADRE peptide 与特定 T 细胞上的泛 HLA-DR 受体结合。PADRE peptide 可插入棘状毛发发育不良相关多瘤病毒 (TSPyV) 病毒蛋白1 (VP1) 或仓鼠多瘤病毒 (HaPyV) 衍生的 VP1中以构建嵌合病毒样颗粒 (VLPs),从而激活树突状细胞和 T 细胞并诱导强烈的免疫应答。PADRE peptide 可用于疫苗研发。

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Custom Peptide Synthesis

PADRE peptide

PADRE peptide Chemical Structure

CAS No. : 161147-59-7

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生物活性

PADRE peptide is a universal peptidic epitope. PADRE peptide binds to pan HLA-DR receptors, present on specific T cells. PADRE peptide can be inserted into trichodysplasia spinulosa-associated polyomavirus (TSPyV) viral protein 1 (VP1) or hamster polyomavirus (HaPyV)-derived VP1 for construction of chimeric virus-like particles (VLPs), therefore activating dendritic cells and T cells and inducing strong immune responses and. PADRE peptide can be used for the development of vaccines[1].

分子量

1347.60

Formula

C65H102N16O15

CAS 号
Sequence

Ala-Lys-Phe-Val-Ala-Ala-Trp-Thr-Leu-Lys-Ala-Ala-Ala

Sequence Shortening

AKFVAAWTLKAAA

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
PADRE peptide
目录号:
HY-P11303
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