2. GPCR/G Protein Immunology/Inflammation
  3. CXCR
  4. PF-06835375

PF-06835375 是一种人源化 IgG1 抗体，选择性靶向 B 细胞、Tfh 细胞和循环 Tfh 样细胞 (cTfh) 上表达的 CXCR5。PF-06835375 可用于系统性红斑狼疮 (SLE) 和类风湿性关节炎 (RA) 的研究。推荐的同型对照是 Human IgG1 kappa, Isotype Control (HY-P99001)。

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PF-06835375

PF-06835375 Chemical Structure

CAS No. : 2796997-12-9

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PF-06835375 相关抗体

Top Publications Citing Use of Products

查看 CXCR 亚型特异性产品:

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CXCR CXCR1 CXCR2 CXCR3 CXCR4 CXCR7 CXCR6

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PF-06835375 is a humanized IgG1 antibody selective against CXCR5 expressed on B cells, Tfh cells, and circulating Tfh-like (cTfh) cells. PF-06835375 can be used for the study of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). The recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001)[1].

同型

Human IgG1 kappa
推荐同型对照抗体
反应种属

Human
IC50 & Target

CXCR5
Clinical Trial
基因 ID

643  [NCBI]

Accession
应用

ELISA, FACS, Functional assay
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PF-06835375 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PF-068353752796997-12-9PF06835375PF 06835375CXCRCXC chemokine receptorsC-X-C motif chemokine receptorsNeutralizing antibodiesInhibitorinhibitorinhibit

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产品名称：
PF-06835375
目录号：
HY-163480
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