1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Picornain 3C

Picornain 3C 是一种在小核糖核酸病毒中发现的蛋白酶,可切割非末端序列的肽键。Picornain 3C 是丝氨酸肽酶胰凝乳蛋白酶和半胱氨酸肽酶木瓜蛋白酶之间的中间产物。Picornain 3C 显示内肽酶活性,选择性切割脊髓灰质炎病毒多聚蛋白中的 Gln-Gly 键,以及在其他小核糖核酸病毒中用 Glu 替代 Gln,用 Ser 或 Thr 替代 Gly。

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Picornain 3C Chemical Structure

Picornain 3C Chemical Structure

CAS No. : 97162-88-4

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生物活性

Picornain 3C is a protease found in picornaviruses, which cleaves peptide bonds of non-terminal sequences. Picornain 3C is an intermediate between the serine peptidase chymotrypsin and the cysteine peptidase papain. Picornain 3C shows endopeptidase activity by selectively cleaving Gln-Gly bonds in the polyprotein of poliovirus and with substitution of Glu for Gln, and Ser or Thr for Gly in other picornaviruses[1].

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产品名称:
Picornain 3C
目录号:
HY-E70018
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