2. Neuronal Signaling
  3. Dopamine Transporter
  4. Piroheptine hydrochloride

Piroheptine hydrochloride 是一种抗胆碱能剂，可抑制多巴胺摄取。Piroheptine hydrochloride 可防止由 MPTP (HY-15608) 诱导的纹状体多巴胺丢失。Piroheptine hydrochloride 可用于帕金森病的研究。

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Piroheptine hydrochloride Chemical Structure

Piroheptine hydrochloride Chemical Structure

CAS No. : 16378-22-6

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Piroheptine hydrochloride 相关抗体

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生物活性

Piroheptine hydrochloride is an anticholinergic agent to inhibit dopamine uptake. Piroheptine hydrochloride prevents loss of striatal dopamine induced by MPTP (HY-15608). Piroheptine hydrochloride can be used for research in Parkinson[1].

体内研究
(In Vivo)

Piroheptine hydrochloride（20 mg/kg；腹腔注射；单剂量，MPTP 注射前 30 分钟）在小鼠模型中抑制 MPTP 的神经毒性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male 8-week-old C57BL/6J mice (20-30 g)[1]
Dosage: 20 mg/kg
Administration: IP; 30 min before MPTP injection (10 mg/kg; 4 times with 1 h interval)
Result: Prevented loss of striatal dopamine.
分子量

339.90

Formula

C22H26ClN
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Piroheptine hydrochloride 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Piroheptine16378-22-6Dopamine TransporterDATSLC6A3Parkinsonanticholinergic agentdopamine uptakeInhibitorinhibitorinhibit

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