2. Anti-infection
  3. Bacterial
  4. PknB-IN-1

PknB-IN-1 (Compound 2) 是 protein kinase B (PknB) 抑制剂 (IC50=14.4 μM)。PknB-IN-1 具有抗霉菌活性，可以抑制结核杆菌 M. tuberculosis H37Rv 的生长 (MIC=6.2 μg/mL)。

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PknB-IN-1 Chemical Structure

PknB-IN-1 Chemical Structure

CAS No. : 1447917-39-6

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PknB-IN-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PknB-IN-1 (Compound 2) is a protein kinase B (PknB) inhibitor (IC50=14.4 μM). PknB-IN-1 shows anti-mycobacterial activity, can inhibit M. tuberculosis H37Rv strain growth (MIC=6.2 μg/mL)[1].

IC50 & Target

IC50: 14.4 μM (PknB)[1]
体外研究
(In Vitro)

PknB-IN-1 (0-100 μM; 60 min) can inhibit M. tuberculosis PknB activity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

PknB-IN-1 相关抗体:

Cell Viability Assay[1]

Cell Line: M. tuberculosis
Concentration: 0-100 μM
Incubation Time: 60 min
Result: Exhibited M. tuberculosis PknB inhibition activity (IC50=7.3 μM).
分子量

390.52

Formula

C25H30N2O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PknB-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PknB-IN-11447917-39-6Bacterialanti-mycobacterial activityM. tuberculosis H37RvInhibitorinhibitorinhibit

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