2. Immunology/Inflammation
  3. PSMA
  4. PSMA-MAL-5

PSMA-MAL-5 是一种 PSMA 配体。PSMA-MAL-5 与 PSMA 的 Cys466 位点共价结合。经 177Lu 和 225Ac 标记的 PSMA-MAL-5 具有较高的放射稳定性和肿瘤摄取率。PSMA-MAL-5 还能有效抑制肿瘤生长。PSMA-MAL-5 可用于前列腺癌的 SPECT/CT 显像和放射性核素治疗。

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PSMA-MAL-5

PSMA-MAL-5 Chemical Structure

CAS No. : 3077205-52-5

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PSMA-MAL-5 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PSMA-MAL-5 is a PSMA ligand. PSMA-MAL-5 covalently binds to Cys466 of PSMA. PSMA-MAL-5 labeled with 177Lu and 225Ac has high radiostability and tumor uptake. PSMA-MAL-5 also effectively inhibits tumor growth. PSMA-MAL-5 can be used for SPECT/CT imaging and radionuclide therapy of prostate cancer[1].

分子量

1363.51

Formula

C65H94N12O20
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PSMA-MAL-5 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PSMA-MAL-53077205-52-5PSMAProstate-specific membrane antigenPSMA ligand177Lu225AcSPECT/CT imagingRadionuclide therapyProstate cancerInhibitorinhibitorinhibit

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目录号：
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