2. 重组蛋白
  3. CD Antigens Receptor Proteins
  4. Stem Cell CD Proteins Epithelial cell CD Proteins
  5. CD318/CDCP1
  6. CDCP1 蛋白, Human (313a.a, HEK293, His)

CDCP1 蛋白, Human (313a.a, HEK293, His)

目录号: HY-P70109
产品使用指南

CDCP1蛋白可能参与细胞粘附和细胞外基质缔合。CDCP1 的磷酸化可能调节锚定与迁移、增殖和分化之间的平衡。CDCP1 蛋白, Human (313a.a, HEK293, His) 是重组的 CDCP1 蛋白，由 HEK293 表达，带有 C-6*His 标签。CDCP1 蛋白, Human (313a.a, HEK293, His) 全长 313 个氨基酸，分子量约为 ~55.0 kDa。

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描述

CDCP1 protein may be involved in cell adhesion and extracellular matrix association. Phosphorylation of CDCP1 may regulate the balance between anchorage and migration, proliferation, and differentiation. CDCP1 Protein, Human (313a.a, HEK293, His) is the recombinant human-derived CDCP1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CDCP1 Protein, Human (313a.a, HEK293, His) is 313 a.a., with molecular weight of ~55.0 kDa.
研究背景

CDCP1 蛋白可能参与细胞粘附以及与细胞外基质的关联。其磷酸化可能在调节锚定和迁移之间的平衡以及增殖和分化方面发挥作用。此外，CDCP1 已显示出作为白血病诊断和鉴定未成熟造血干细胞亚群的新型标记物的前景。它属于四跨膜蛋白网，与肿瘤的进展和转移有关。CDCP1 与多种蛋白质相互作用，包括 CDH2/N-钙粘蛋白、CDH3/P-钙粘蛋白、SDC1/syndecan-1、SDC4/syndecan-4、丝氨酸蛋白酶 ST14/MT-SP1 以及 SRC 和 PRKCG/蛋白激酶 C gamma ，表明它参与各种细胞过程和信号通路。
种属

Human
表达系统

HEK293
标签

C-6*His
蛋白编号

Q9H5V8-3 (F30-S342)
基因 ID
蛋白结构
N-term
CDCP1 (F30-S342)
Accession # Q9H5V8-3
6*His
C-term
同用名
rHuCUB domain-containing protein 1/CDCP1, His; CUB domain-containing protein 1; Membrane glycoprotein gp140; Subtractive immunization M plus HEp3-associated 135 kDa protein; SIMA135; Transmembrane and associated with src kinases; CD318; TRASK
氨基酸序列

FEIALPRESNITVLIKLGTPTLLAKPCYIVISKRHITMLSIKSGERIVFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPTLNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTHSISGRIDATVVRIGTFCSNGTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPEGFPEDELMTWQFVVPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDKQPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQHPQNES

分子量

Approximately 55.0 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

CDCP1 Protein, Human (313a.a, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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