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  2. CDCP1 - CUB domain containing protein 1 Gene

CDCP1 - CUB domain containing protein 1 Gene

中文名称:含 CUB 结构域蛋白 1

种属: Homo sapiens

同用名: CD318; TRASK; SIMA135

基因 ID: 64866 | 基因类型: protein coding

关于 CDCP1

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:45,082,277-45,146,482 (from NCBI)

This gene has 3 transcripts (splice variants) and 269 orthologues. Broad expression in esophagus (RPKM 12.2), skin (RPKM 11.1) and 15 other tissues.

功能概要

该基因编码一种跨膜蛋白,该蛋白包含三个细胞外 CUB 结构域,并充当 Src 家族激酶的底物。该蛋白在参与肿瘤侵袭和转移的细胞事件的酪氨酸磷酸化依赖性调节中发挥作用。可变剪接导致该基因的多个转录变体。[RefSeq 提供,2013 年 5 月]

This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]

CDCP1 基因产物(2)

mRNA Protein Name
NM_022842.5 NP_073753.3 CUB domain-containing protein 1 isoform 1 precursor
NM_178181.3 NP_835488.1 CUB domain-containing protein 1 isoform 2 precursor
蛋白主名 其他名称

CUB domain-containing protein 1

membrane glycoprotein gp140

重组 CDCP1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70109 CDCP1 Protein, Human (313a.a, HEK293, His) Q9H5V8-3 (F30-S342) ≥95%
HY-P77891 CDCP1 Protein, Human (637a.a, HEK293, His) Q9H5V8 (F30-L666) ≥95%
HY-P77892 CDCP1 Protein, Human (HEK293, Fc) Q9H5V8 (F30-L666) ≥95%
HY-P77893 CDCP1 Protein, Human (Biotinylated, HEK293, His-Avi) Q9H5V8 (F30-L666) ≥95%
HY-P700969 CDCP1 Protein, Human (339a.a, HEK293, His) Q9H5V8-1 (F30-R368) ≥95%

关联疾病

疾病名称 别名
Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Susceptibility To

Lung Cancer, Protection Against

Adenocarcinoma Of Lung, Somatic

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris CDCP1 VGNC VGNC:39018
Macaca mulatta CDCP1 VGNC VGNC:70849
Rattus norvegicus CDCP1 RGD RGD:1305578
Felis catus CDCP1 VGNC VGNC:60671
Bos taurus CDCP1 VGNC VGNC:27089
Mus musculus CDCP1 MGD MGI:2442010
Macaca fascicularis CDCP1 NCBI
Others CDCP1 NCBI