IL-27R alpha/TCCR 蛋白, Human (HEK293, His)

IL-27R alpha/TCCR Protein, acting as a receptor for IL27, relies on IL6ST/GP130 for signal transduction, activating STAT3 and STAT1. It is also part of a complex with IL6ST/GP130 and CNTFR, functioning as a receptor for the neuroprotective peptide humanin. IL-27R alpha/TCCR is implicated in regulating Th1-type immune responses and participating in innate defense mechanisms. This receptor is a key component of a complex with IL6ST/GP130, IL27RA/WSX1, and CNTFR, interacting with the neuroprotective peptide humanin. IL-27R alpha/TCCR Protein, Human (HEK293, His) is the recombinant human-derived IL-27R alpha/TCCR protein, expressed by HEK293, with C-His labeled tag. The total length of IL-27R alpha/TCCR Protein, Human (HEK293, His) is 483 a.a., with molecular weight of 75-105 kDa.

IL-27R α/TCCR 是 IL27 的一种受体，依赖 IL6ST/GP130 促进响应 IL27 的信号转导，通过 STAT3 和 STAT1 途径发挥作用。该受体还参与神经保护肽护脑素的识别，与 IL6ST/GP130 和 CNTFR 形成复合物。除了参与 Th1 型免疫反应的调节之外，IL-27R α/TCCR 还与先天防御机制相关。它形成包含 IL6ST/GP130、IL27RA/WSX1 和 CNTFR 的受体复合物的一部分，并且该复合物与神经保护肽人肽相互作用。

Human

HEK293

C-His

Q6UWB1 (G34-K516)

9466  [NCBI]

75-105 kDa

Greater than 90% as determined by reducing SDS-PAGE.

溶液

Supplied as a 0.22μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.