Neuropilin-2 蛋白, Mouse (HEK293, His)

Neuropilin-2 protein, a high affinity receptor, binds to semaphorins 3C and 3F, VEGF-165, VEGF-145, and PLGF-2.It forms a heterodimer with NRP1 and also interacts with PLXNB1, similar to NRP1. Neuropilin-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Neuropilin-2 protein, expressed by HEK293 , with C-His labeled tag.

Neuropilin-2 蛋白是信号蛋白 3C 和 3F、VEGF 的 VEGF-165 和 VEGF-145 亚型以及 PGF 的 PLGF-2 亚型的高亲和力受体。它与 NRP1 形成异二聚体，并且与 NRP1 类似，也与 PLXNB1 结合。

Measured by its binding ability in a functional ELISA. Immobilized Human VEGF165 (HY-P7110A) at 5 μg/mL (100 μL/well) in the presence of 2 μg/mL of heparin on the plate can bind Mouse Neuropilin-2. The Kd for this effect is 0.9025 nM.

Mouse

HEK293

C-His

O35375 (M1-P864)

18187  [NCBI]

Partial

Approximately 96.5 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.