2. Gene
  3. Nrp2 - neuropilin 2 Gene

Nrp2 - neuropilin 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Np2; Np-2; Npn2; Npn-2; 1110048P06Rik

基因 ID: 18187 | 基因类型: protein coding

关于 Nrp2

功能概要

Enables semaphorin receptor activity. Involved in several processes, including nervous system development; outflow tract septum morphogenesis; and ventral trunk neural crest cell migration. Acts upstream of or within several processes, including axon guidance; cellular response to leukemia inhibitory factor; and neural crest cell migration. Located in axon. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; embryo mesenchyme; and limb. Used to study autism spectrum disorder. Orthologous to human NRP2 (neuropilin 2). [provided by Alliance of Genome Resources, Apr 2022]

Nrp2 基因产物(6)

mRNA Protein Name
NM_001077403.1 NP_001070871.1 neuropilin-2 isoform 1 precursor
NM_001077404.1 NP_001070872.1 neuropilin-2 isoform 2 precursor
NM_001077405.1 NP_001070873.1 neuropilin-2 isoform 4 precursor
NM_001077406.1 NP_001070874.1 neuropilin-2 isoform 5 precursor
NM_001077407.1 NP_001070875.1 neuropilin-2 isoform 6 precursor
NM_010939.2 NP_035069.2 neuropilin-2 isoform 3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10520994 MGI
enables semaphorin receptor activity IDA
IDA: 通过直接分析推断
15239958 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in axon extension involved in axon guidance IMP
IMP: 通过突变表型推断
22790009 MGI
acts upstream of or within axon guidance IMP
IMP: 通过突变表型推断
15814794 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
involved in dorsal root ganglion morphogenesis IMP
IMP: 通过突变表型推断
19386662 MGI
involved in facial nerve structural organization IMP
IMP: 通过突变表型推断
18356247 MGI
involved in facioacoustic ganglion development IMP
IMP: 通过突变表型推断
18356247 MGI
involved in gonadotrophin-releasing hormone neuronal migration to the hypothalamus IMP
IMP: 通过突变表型推断
21059704 MGI
acts upstream of or within heart development IGI
IGI: 通过遗传相互作用推断
12852851 MGI
acts upstream of or within negative chemotaxis IGI
IGI: 通过遗传相互作用推断
16319111 MGI
acts upstream of or within negative chemotaxis IMP
IMP: 通过突变表型推断
15814794 MGI
involved in nerve development IMP
IMP: 通过突变表型推断
22790009 MGI
involved in neural crest cell migration involved in autonomic nervous system development IMP
IMP: 通过突变表型推断
18356247 MGI
involved in neuron migration IMP
IMP: 通过突变表型推断
21059704 MGI
involved in outflow tract septum morphogenesis IGI
IGI: 通过遗传相互作用推断
26053665 MGI
involved in regulation of postsynapse organization IDA
IDA: 通过直接分析推断
20010807 MGI
involved in regulation of postsynapse organization IMP
IMP: 通过突变表型推断
20010807 MGI
involved in semaphorin-plexin signaling pathway IMP
IMP: 通过突变表型推断
22790009 MGI
involved in sensory neuron axon guidance IMP
IMP: 通过突变表型推断
18356247 MGI
involved in sympathetic ganglion development IMP
IMP: 通过突变表型推断
22790009 MGI
involved in sympathetic neuron projection extension IMP
IMP: 通过突变表型推断
22790009 MGI
involved in sympathetic neuron projection guidance IMP
IMP: 通过突变表型推断
22790009 MGI
involved in trigeminal ganglion development IMP
IMP: 通过突变表型推断
18356247 MGI
acts upstream of or within trunk neural crest cell migration IMP
IMP: 通过突变表型推断
16319111 MGI
involved in ventral trunk neural crest cell migration IMP
IMP: 通过突变表型推断
19386662 MGI
involved in vestibulocochlear nerve structural organization IMP
IMP: 通过突变表型推断
18356247 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
15677725 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
20010807 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
20010807 MGI
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
25143608 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neuropilin-2

vascular endothelial cell growth factor 165 receptor 2

重组 Nrp2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73315 Neuropilin-2 Protein, Mouse (HEK293, His) O35375 (M1-P864) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P990782 Efzofitimod / Phase 3
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09205 NELL2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS09580 NRP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17411 Nrp2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23865 Nrp2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nrp2 NCBI NCBI:8828
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