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  3. Transferrin 蛋白, Mouse (HEK293, Fc)

Transferrin 蛋白, Mouse (HEK293, Fc)

目录号: HY-P73581
产品使用指南

转铁蛋白是一种重要的铁结合转运蛋白,它将两个 Fe(3+) 离子与一个阴离子(通常是碳酸氢根)结合起来。其主要作用是将铁从吸收场所输送到储存和利用场所。Transferrin 蛋白, Mouse (HEK293, Fc) 是重组的 转铁蛋白,由 HEK293 表达,带有 C-hFc 标签。Transferrin 蛋白, Mouse (HEK293, Fc) 全长 697 个氨基酸,分子量约为 ~102 kDa。

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描述

Transferrin is an important iron-binding transport protein that combines two Fe(3+) ions with an anion, usually bicarbonate. Its main function is to transport iron from the site of absorption to the site of storage and utilization. Transferrin Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Transferrin protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Transferrin Protein, Mouse (HEK293, Fc) is 697 a.a., with molecular weight of ~102 kDa.

研究背景

转铁蛋白是一种关键的铁结合转运蛋白,具有结合两个 Fe(3+) 离子和一个阴离子(通常是碳酸氢根)的能力。它的主要职责在于促进铁从吸收位点和血红素降解运输到指定的体内储存和利用位置。除了在铁稳态中的基本作用之外,血清转铁蛋白还可能在促进细胞增殖方面发挥作用。转铁蛋白的结构为单体,其多方面功能强调了其在协调铁分布和细胞过程的复杂平衡方面的重要性,这对于整体生理健康至关重要。

种属

Mouse

表达系统

HEK293

标签

C-hFc

蛋白编号

Q921I1 (M1-H697)

基因 ID

22041  [NCBI]

蛋白结构
N-term
Transferrin (M1-H697)
Accession # Q921I1
hFc
C-term
同用名
Serotransferrin; Transferrin; Beta-1 metal-binding globulin; Siderophilin; TF; TRF
分子量

Approximately 102 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

Transferrin Protein, Mouse (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Transferrin Protein, Mouse (HEK293, Fc)
目录号:
HY-P73581
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