1. 重组蛋白
  2. Enzymes & Regulators
  3. Protein Kinase Inhibitor Peptide (PKI)
  4. TRIB2 蛋白, Human (sf9, His-GST)

TRIB2 蛋白, Human (sf9, His-GST)

目录号: HY-P74492
产品使用指南

TRIB2 蛋白通过与 MAPK 激酶相互作用来调节 MAP 激酶激活,充当无内在激酶活性的调节剂。强调其在微调 MAP 激酶信号通路中的作用。TRIB2 蛋白, Human (sf9, His-GST) 是重组的 TRIB2 蛋白,由 Sf9 insect cells 表达,带有 C-His, N-GST 标签。TRIB2 蛋白, Human (sf9, His-GST) 全长 343 个氨基酸,分子量约为 ~66 kDa。

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描述

TRIB2 protein regulates MAP kinase activation by interacting with MAPK kinase, acting as a regulator without intrinsic kinase activity. Emphasizing its role in fine-tuning the MAP kinase signaling pathway. TRIB2 Protein, Human (sf9, His-GST) is the recombinant human-derived TRIB2 protein, expressed by Sf9 insect cells , with C-His, N-GST labeled tag. The total length of TRIB2 Protein, Human (sf9, His-GST) is 343 a.a., with molecular weight of ~66 kDa.

研究背景

尽管 TRIB2 蛋白本身缺乏内在的激酶活性,但它通过与 MAPK 激酶相互作用来对 MAP 激酶的激活进行调节控制。这种相互作用强调了 TRIB2 作为调节剂而不是直接激酶的作用,表明它参与微调 MAP 激酶信号通路。此外,TRIB2 与 COP1 发生特定的相互作用,进一步扩大其在细胞过程中的潜在调节影响。这些相互作用的功能意义凸显了 TRIB2 作为协调细胞信号级联的关键参与者,并值得进一步探索其复杂的调节机制。

种属

Human

表达系统

Sf9 insect cells

标签

C-His;N-GST

蛋白编号

Q92519 (M1-N343)

基因 ID
蛋白结构
N-term
GST
TRIB2 (M1-N343)
Accession # Q92519
His
C-term
同用名
Tribbles homolog 2; TRB-2; TRIB2; TRB2
分子量

Approximately 66 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

TRIB2 Protein, Human (sf9, His-GST) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
TRIB2 Protein, Human (sf9, His-GST)
目录号:
HY-P74492
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