2. Epigenetics
  3. MicroRNA
  4. rno-miR-122-5p agomir

rno-miR-122-5p agomir 是一种经过特殊化学修饰的 miRNA 模拟物，miRNA 成熟链全链进行甲氧基修饰，在 5'端和 3'端分别有 2 个和 4 个硫代骨架修饰，并在 3'端连接有高亲和性胆固醇修饰。miRNA agomir 可以模拟内源性 miRNA，上调 miRNA 活性。与普通模拟物相比，miRNA agomir 在动物实验中具有更高的稳定性和抑制效果，更易通过细胞膜、组织间隙而富集于靶细胞。

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rno-miR-122-5p agomir

rno-miR-122-5p agomir Chemical Structure

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rno-miR-122-5p agomir 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

rno-miR-122-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

rno-miR-122-5p agomir 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

rno-miR-122-5p agomirMicroRNAmiRNAInhibitorinhibitorinhibit

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产品名称：
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