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  2. ROR
  3. ROR agonist-1

ROR agonist-1 

目录号: HY-128353
产品使用指南

ROR agonist-1 是一种有效、口服可利用的视黄酸受体相关孤儿受体 C2 (RORC2) 反向激动剂,抑制人类原始 TH 17 细胞产生 IL-17A 的 pIC50 为7.5。

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ROR agonist-1 Chemical Structure

ROR agonist-1 Chemical Structure

CAS No. : 2361528-74-5

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Description

ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5[1].

IC50 & Target

pIC 50: 7.5 (human primary TH 17 cells)[1]

Molecular Weight

526.45

Formula

C₂₁H₂₀F₆N₂O₅S

CAS No.

2361528-74-5

SMILES

O=C([C@H](NC(C)=O)C1=CC=C(S(=O)(CC)=O)C=C1)NC2=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C2

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

ROR agonist-1ROR agonist1ROR agonist 1RORRAR-related orphan receptorInhibitorinhibitorinhibit

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产品名称:
ROR agonist-1
目录号:
HY-128353
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