1. Anti-infection
  2. Fungal
  3. Rustmicin

Rustmicin  (Synonyms: Galbonolide A)

目录号: HY-113637
产品使用指南

Rustmicin (Galbonolide A) 是一种有效的抗真菌剂。Rustmicin 抑制肌醇磷酸神经酰胺合酶。Rustmicin 具有抗真菌活性。

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Rustmicin Chemical Structure

Rustmicin Chemical Structure

CAS No. : 100227-57-4

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Rustmicin (Galbonolide A) is a potent antifungal agent. Rustmicin inhibits inositol phosphoceramide synthase. Rustmicin shows antifungal activity[1].

体外研究
(In Vitro)

Rustmicin (0-32 µg/mL; 24-48 h) 显示抗真菌活性,对 Cryptococcus neoformans MY1051, Cryptococcus neoformans MY1146, Cryptococcus neoformans MY2061, Cryptococcus neoformans MY2062, C. parapsilosis (MY1010), C. pseudotropicalis (MY2099), C. krusei (MY549), C. tropicalis (MY1012) 菌株的 MIC 值分别为 0.002, 0.001, 0.0001, 0.0002, 0.015, 0.015, 0.031, 0.031 µg/mL[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Rustmicin (0、10、20、40、80 mg/kg;腹腔注射;每天两次,持续 4 天) 在隐球菌病小鼠模型中显示出抗真菌活性[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: DBA/2N mice (Cryptococcus neoformans MY2061)[1]
Dosage: 0, 10, 20, 40, 80 mg/kg
Administration: I.p.; twice daily for 4 days
Result: Showed a dose-dependent reduction in colony-forming units isolated from spleen and brain tissue of mice, with the ED99 value of 29 mg/kg for both tissues.
分子量

380.48

Formula

C21H32O6

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Rustmicin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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