2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. (S,R,S)-AHPC-PEG2-NH2 dihydrochloride

(S,R,S)-AHPC-PEG2-NH2 dihydrochloride  (Synonyms: VH032-PEG2-NH2 dihydrochloride)

目录号: HY-103603B
COA 产品使用指南

摩尔计算器

(S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-PEG2-NH2 dihydrochloride) 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 (S,R,S)-AHPC 的 VHL 配体和 2 个单元 PEG linker。可用于合成 PROTAC 分子。

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(S,R,S)-AHPC-PEG2-NH2 dihydrochloride Chemical Structure

(S,R,S)-AHPC-PEG2-NH2 dihydrochloride Chemical Structure

CAS No. : 2341796-76-5

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规格 价格 是否有货 数量
5 mg ￥437
In-stock
10 mg ￥700
In-stock
25 mg ￥1400
In-stock
50 mg ￥2200
In-stock
100 mg ￥3100
In-stock
200 mg   询价  
500 mg   询价  

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Other Forms of (S,R,S)-AHPC-PEG2-NH2 dihydrochloride:

(S,R,S)-AHPC-PEG2-NH2 dihydrochloride 相关抗体

Top Publications Citing Use of Products

查看 E3 Ligase Ligand-Linker Conjugates 亚型特异性产品:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-PEG2-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs[1].

IC50 & Target

VHL

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(S,R,S)-AHPC-PEG2-NH2 dihydrochloride 相关抗体:
分子量

648.64

Formula

C28H43Cl2N5O6S
CAS 号
性状

固体

颜色

Yellow to green

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料

纯度: ≥95.0%

COA (270 KB) HNMR (137 KB)

产品使用指南 (1538 KB)
参考文献

(S,R,S)-AHPC-PEG2-NH2 dihydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S,R,S)-AHPC-PEG2-NH22341796-76-5VH032-PEG2-NH2E3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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目录号：
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