1. Screening Libraries
  2. MAPK Compound Library

MAPK 化合物库 - MAPK Compound Library

Cat. No.: HY-L010
Library Contents: XLSX PDF SDF

MAPK 家族在复杂的细胞增殖、分化、发育、转化、凋亡等过程中发挥重要作用。在哺乳动物细胞中,发现有四种类型的 MAPK 级联通路,ERK1/2 信号通路,JNK 信号通路,p38 激酶信号通路和 ERK5 信号通路,他们会对不同的信号产生反应。MAPK 通路包含一组三级磷酸化依赖的激酶,包括 MAPK 激酶激酶 (MKKK) 、MAPK 激酶 (MKK) 和 MAPK。MAPK 信号通路参与多种疾病的发生,如阿尔茨海默病 (AD),帕金森病 (PD),肌萎缩性脊髓侧索硬化症 (ALS) 和各种癌症。

MCE 收集的 214 种 MAP K信号相关抑制剂,是 MAPK 相关的药物筛选和疾病研究的有用工具。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
30 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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50 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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100 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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2 × 100 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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  • Description

  • Product Details

  • Composition

  • Documentation

Description
& Advantages

•   A unique collection of 214 MAPK signaling inhibitors for high throughput screening (HTS) and high content screening (HCS).

•   Targets such as ERK, JNK, MEK, p38 MAPK, Raf, RSK, etc.

•   A useful tool for MAPK-related drug discovery and disease research.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some inhibitors have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 214 MAPK/ERK signaling related compounds supplied as pre-dissolved DMSO solutions or Solid .
Solution: 210 compounds supplied in 10 mM solution, 4 compounds supplied in 2 mM solution.
Container:
96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition

MAPK Compound Library

Source: MedChem Express

Contents of MAPK Compound Library
Documentation

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    产品名称:
    MAPK Compound Library
    目录号:
    HY-L010
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack