2. Neuronal Signaling
  3. Amyloid-β
  4. SQ-3

SQ-3 是一种喹啉类似物，对 α-syn 聚合体 (Ki=39.3 nM) 具有中等选择性，并高于 β-淀粉样蛋白 (Aβ) 聚合体，Ki 分别为 39.3 nM 和 230 nM。[18F]SQ3 具有 α-syn 成像探针的先导化合物的基本性能。

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SQ-3 Chemical Structure

SQ-3 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Customer Review

SQ-3 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SQ-3 is a quinoline analogue, displays moderate selectivity for α-syn aggregates (Ki=39.3 nM) over β-amyloid (Aβ) aggregates (Ki=230 nM). [18F]SQ3 has basic properties as a lead compound for the development of a useful α-syn imaging probe[1].

体内研究
(In Vivo)

SQ-3 ([18F]SQ3) exhibits high uptake (2.08% ID/g at 2 min after intravenous injection) into a normal mouse brain[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

336.40

Formula

C21H21FN2O
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SQ-3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SQ-3SQ3SQ 3Amyloid-ββ-amyloid peptideAβAbetasynucleinopathiesα-synucleinimaging probeα-synInhibitorinhibitorinhibit

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