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SW203668 是苯并噻唑类化合物,对肺癌细胞系显示出抗肿瘤活性 (IC50=0.022-0.116 μM)。

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SW203668 Chemical Structure

SW203668 Chemical Structure

CAS No. : 1673556-40-5

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规格 价格 是否有货 数量
5 mg ¥3110
3 - 4 周
10 mg   询价  
50 mg   询价  

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SW203668 is a benzothiazole compound, shows anti-tumor activity against lung cancer cell lines (IC50=0.022-0.116 μM)[1].

体外研究
(In Vitro)

SW203668 (0.1, 0.3, 1, 3,和 10 μM) 有 2 个苯并噻唑对映体,(+)-SW203668 比 (-)-SW203668 更能与 p37/p30 结合[1]
SW203668 (1 nM-10 μM; 2 d) 抑制 H2122 细胞生长,IC50 分别为 0.029 μM ((+)-SW203668) 和 0.007 μM ((-)-SW203668)[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

SW203668 (25 mg/kg; 腹腔注射; 单次剂量) 在小鼠血浆中半衰期为 8 小时,(6mg /kg, 20mg /kg; 腹腔注射; 每天1次,持续 15 天) 对 CD-1 小鼠低毒[1]
SW203668 (20 mg/kg; 腹腔注射; 每天 1 次,持续 14 天) 能够保存皮脂细胞,并显著增加小鼠的皮脂细胞数量[1]
SW203668 (20 mg/kg; 腹腔注射; 每天1次,持续 14 天) 对含有H2122细胞来源的肿瘤异种移植的免疫缺陷型非肥胖糖尿病严重联合免疫缺陷(NOD-SCID)小鼠显示出抗肿瘤效果[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

389.47

Formula

C22H19N3O2S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

SW203668 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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SW203668
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HY-124084
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