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  3. THK-523

THK-523 

目录号: HY-100723
产品使用指南

THK-523 在体内外对 tau 具有高亲和力和选择性。18F-THK-523 是一种有效的 tau 成像放射性示踪剂。18F-THK-523 是一种有效的体内 tau 成像配体,可用于研究阿尔茨海默症。

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THK-523 Chemical Structure

THK-523 Chemical Structure

CAS No. : 1573029-17-0

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生物活性

THK-523 has demonstrated its high affinity and selectivity for tau pathology both in vitro and in vivo. 18F-THK523 is a potent tau imaging radiotracer. 18F-THK523 is a potent in vivo tau imaging ligand for Alzheimer's disease[1].

体内研究
(In Vivo)

THK-523 crosses the blood–brain barrier in mice and the in vivo retention rate in the brain of Tau transgenic mice increased[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Brain of tau transgenic mice[1]
Dosage: 0.35 μg/kg
Administration: Intravenous injection;25-30 mins
Result: Overexpressed Tau in brain.
分子量

282.31

Formula

C17H15FN2O

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

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产品名称:
THK-523
目录号:
HY-100723
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