1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. GABA Receptor
  3. Tiagabine hydrochloride hydrate

Tiagabine hydrochloride hydrate (Synonyms: NO050328 hydrochloride hydrate; NO328 hydrochloride hydrate; TGB hydrochloride hydrate)

目录号: HY-B0696B
产品使用指南

Tiagabine hydrochloride hydrate 是一种有效、选择性的 GABA uptake 抑制剂,为抗惊厥剂;在突触体、神经元和神经胶质中,能够抑制 [3H]GABA 的摄取,IC50 值分别为 67,446 和 182 nM。

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Tiagabine hydrochloride hydrate Chemical Structure

Tiagabine hydrochloride hydrate Chemical Structure

CAS No. : 145821-57-4

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Description

Tiagabine hydrochloride hydrate is a potent and selective GABA uptake inhibitor, used as an anticonvulsant agent, with IC50s of 67, 446 and 182 nM for [3H]GABA uptake in Synaptosomes, Neurons and Glia, respectively[1].

Clinical Trial
Molecular Weight

430.02

Formula

C₂₀H₂₈ClNO₃S₂

CAS No.

145821-57-4

SMILES

O=C([C@H]1CN(CC/C=C(C2=C(C)C=CS2)/C3=C(C)C=CS3)CCC1)O.[H]Cl.O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Tiagabine hydrochloride hydrate
目录号:
HY-B0696B
需求量:

Tiagabine hydrochloride hydrate

Cat. No.: HY-B0696B