1. Apoptosis
  2. Apoptosis
  3. Trihexyl phosphate

Trihexyl phosphate 是一种有机磷酸酯阻燃剂。Trihexyl phosphate 会导致线粒体损伤,并诱导 CHO 细胞凋亡 (apoptosis)。Trihexyl phosphate 以剂量依赖性方式促进人乳腺癌细胞 (MCF-7) 增殖,并通过 ERα 非依赖途径发挥雌激素样作用。

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Trihexyl phosphate

Trihexyl phosphate Chemical Structure

CAS No. : 2528-39-4

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  • 生物活性

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  • 参考文献

生物活性

Trihexyl phosphate is an organophosphate flame retardant. Trihexyl phosphate causes mitochondrial impairment and induces cell apoptosis in CHO cells. Trihexyl phosphate promotes the proliferation of human breast cancer cells (MCF-7) in a dose-dependent manner and exerts estrogenicity via ERα-independent pathways[1].

分子量

350.47

Formula

C18H39O4P

CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
纯度 & 产品资料
参考文献

Trihexyl phosphate 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Trihexyl phosphate
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