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Trx-red  (Synonyms: NBL-SS perchlorate)

目录号: HY-D1254 纯度: 96.58%
COA 产品使用指南

Trx-red (NBL-SS perchlorate) 是衍生自尼罗蓝色荧光团的红色发射荧光探针。Trx-red 用于在活细胞和体内选择性地对硫氧还蛋白 (thioredoxin, Trx) 成像 (λex=615 nm, λem=661 nm)。

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Trx-red Chemical Structure

Trx-red Chemical Structure

CAS No. : 2368978-96-3

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
1 mg ¥1590
In-stock
5 mg ¥3500
In-stock
10 mg ¥5800
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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm)[1].

体外研究
(In Vitro)

Trx-red (NBL-SS) displayed multiple favorable properties, such as red emission, fast response, and high fluorescence signal. Thioredoxin (Trx) is a ubiquitous redox-regulating protein essentially involved in cell growth, differentiation, and death[1].
When HeLa cells are incubated with Trx-red (NBL-SS; 5 μM; 0-30 min), a clear time-dependent increase of the fluorescence is observed[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Trx-red (NBL-SS; 10 μM; 30 min) is also suitable to image thioredoxin in 6 day-old zebrafish larvae[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

714.16

Formula

C29H32ClN3O12S2

CAS 号
性状

液体

颜色

Purple to purplish red

Emission (Em)

660

Excitation (Ex)

615

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro: 

DMSO 中的溶解度 : 50 mg/mL (70.01 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.4002 mL 7.0012 mL 14.0025 mL
5 mM 0.2800 mL 1.4002 mL 2.8005 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Trx-red 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4002 mL 7.0012 mL 14.0025 mL 35.0062 mL
5 mM 0.2800 mL 1.4002 mL 2.8005 mL 7.0012 mL
10 mM 0.1400 mL 0.7001 mL 1.4002 mL 3.5006 mL
15 mM 0.0933 mL 0.4667 mL 0.9335 mL 2.3337 mL
20 mM 0.0700 mL 0.3501 mL 0.7001 mL 1.7503 mL
25 mM 0.0560 mL 0.2800 mL 0.5601 mL 1.4002 mL
30 mM 0.0467 mL 0.2334 mL 0.4667 mL 1.1669 mL
40 mM 0.0350 mL 0.1750 mL 0.3501 mL 0.8752 mL
50 mM 0.0280 mL 0.1400 mL 0.2800 mL 0.7001 mL
60 mM 0.0233 mL 0.1167 mL 0.2334 mL 0.5834 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号:
HY-D1254
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