2. Anti-infection
  3. Influenza Virus
  4. VF-57a

VF-57a (Compound 23) 是一种甲型流感病毒 (IAV) 融合 (Influenza A virus (IAV) fusion) 抑制剂。VF-57 对真正的 A/H1N1 病毒具有强效的抗病毒活性，对 A/H1N1 PR8 和 A/H1N1 Virg09 毒株的 EC50 分别为 0.92 μM 和 0.31 μM。VF-57 显著抑制 HA 介导的 A/H1N1 和 A/H5N1 假病毒的细胞入侵，并在 pH 5.2 时阻止 HA 重新折叠。VF-57a 可用于 IAV 感染研究。

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VF-57a

VF-57a Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Customer Review

VF-57a 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

VF-57a (Compound 23) is an Influenza A virus (IAV) fusion inhibitor. VF-57 has potent antiviral activities against authentic A/H1N1 virus with EC50s of 0.92 and 0.31 μM for the A/H1N1 PR8 and A/H1N1 Virg09 strains, respectively. VF-57 significantly inhibits HA-mediated cell entry of A/H1N1- and A/H5N1-pseudoviruses, prevents the HA refolding at pH 5.2. VF-57a can be used for IAV infections research[1].

分子量

347.78

Formula

C15H13ClF3NOS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

VF-57a 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VF-57aInfluenza VirusInfluenza A virusIAV fusionMDCK cellsHA refoldingIAV infectionsInhibitorinhibitorinhibit

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