2. Peptides
  3. Xenopsin-Related Peptide 2

Xenopsin-Related Peptide 2  (Synonyms: XP-2)

目录号: HY-P3837
产品使用指南

摩尔计算器

Xenopsin-Related Peptide 2 (XP-2) 是两栖动物 Xenopsin (HY-P0253) 的鸟类对应物。Xenopsin-Related Peptide 2 显示出从分离的大鼠肥大细胞释放组胺的能力，和合成的 Bradykinin (HY-P0206) 一样有效。

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Custom Peptide Synthesis

Xenopsin-Related Peptide 2 Chemical Structure

Xenopsin-Related Peptide 2 Chemical Structure

CAS No. : 117442-29-2

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Xenopsin-Related Peptide 2 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Xenopsin-Related Peptide 2 (XP-2) is an avian counterpart to amphibian Xenopsin (HY-P0253). Xenopsin-Related Peptide 2 displays abilities to release histamine from isolated rat mast cells and is as effective as synthetic Bradykinin (HY-P0206)[1].

体外研究
(In Vitro)

Synthetic and native preparations of Xenopsin-Related Peptide 2 (XP-2) increases vascular permeability in rats and released histamine from isolated rat mast cells at submicromolar concentrations[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Xenopsin-Related Peptide 2 相关抗体:
体内研究
(In Vivo)

Xenopsin-Related Peptide 2 (XP-2) (0.3-3000 nM; intradermally; 50 μL) induces skin vascular permeability in rats[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rats weighing 300-400 g[1]
Dosage: 0.3-3000 nM
Administration: Intradermal injection, 50 μL
Result: Increased skin vascular permeability in a dose-dependent manner.
分子量

1193.44

Formula

C60H88N16O10
CAS 号
Sequence Shortening

FHPKRPWIL
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料
参考文献

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Xenopsin-Related Peptide 2117442-29-2XP-2XP2XP 2Othersavian counterpartamphibian XenopsinBradykininInhibitorinhibitorinhibit

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产品名称：
Xenopsin-Related Peptide 2
目录号：
HY-P3837
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