2. Antibody-drug Conjugate/ADC Related Apoptosis
  3. Antibody-Oligonucleotide Conjugates (AOCs) Transferrin Receptor
  4. Zeleciment rostudirsen

Zeleciment rostudirsen  (Synonyms: DYNE-251)

目录号: HY-177485
产品使用指南 技术支持

Zeleciment rostudirsen (DYNE-251) 由一种寡核苷酸 Rostudirsen (HY-177484) 与抗体 Zeleciment (HY-P990780) 结合而成。Zeleciment 能够与肌肉中高度表达的转铁蛋白受体 1 (TfR1) 结合。Zeleciment rostudirsen 可靶向肌肉组织，并促进细胞内51 号外显子跳跃，使肌肉细胞能够生成接近完整长度的肌营养不良蛋白。

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Zeleciment rostudirsen

Zeleciment rostudirsen Chemical Structure

CAS No. : 2725863-42-1

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Zeleciment rostudirsen 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Zeleciment rostudirsen (DYNE-251) consists of a phosphorodiamidate morpholino oligomer (PMO) Rostudirsen (HY-177484) conjugated to a fragment antibody (Fab), Zeleciment (HY-P990780), which binds to the transferrin receptor 1 (TfR1) that is highly expressed in muscle. It is designed to enable targeted muscle tissue delivery and promote exon skipping in the nucleus, allowing muscle cells to create internally shortened, near full-length dystrophin protein.

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纯度 & 产品资料
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Zeleciment rostudirsen 相关分类

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Keywords:

Zeleciment rostudirsen2725863-42-1DYNE-251DYNE251DYNE 251Antibody-Oligonucleotide Conjugates (AOCs)Transferrin ReceptorTfRCD71Inhibitorinhibitorinhibit

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